Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Oct 26;36:150. doi: 10.1186/s13046-017-0617-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 6 — Upregulation of miR-143 and miR-107 by Mithramycin A via p53 activation decreases MSI-2 levels and suppresses invasion and proliferation of CC cells. a, Western blotting analysis of p53, p21 and MSI-2 in CC cells treated with Mithramycin A (MM). b, miR-143 and miR-107 expression in CC cells treated with Mithramycin A. c, Western blotting analysis of p53 and MSI-2 in CC cells transfected with control or p53 expression vector. d, qRT-PCR analysis of miR-143 and miR-107 in CC cells transfected with control or p53 expression vector. e, Representative images of transwell invasion assays and sphere formation assays (upper panel). Quantification of invasion, proliferation and sphere formation of CC cells treated with Mithramycin A or DMSO (lower panel). ^* P < 0.05