Table 2.

Clinical, radiographical, laboratory and genetic data for CGD of the 3 patients

CGD patient	Case 1	Case 2	Case 3
Antecedent history	Pneumonia at 3 months old, eczema and seasonal rhinitis at one year old	Eczema and seasonal rhinitis at 3 years old	Perianal abscesses and eczema at 3 months old
Igs	IgG 12.2 g/L, IgM1.72 g/L, IgA2.59 g/L, IgE 598.9 IU/mL	IgG 26.8 g/L, IgM1.12 g/L, IgA4.55 g/L, IgE 3000 IU/mL	IgG 26.6 g/L, IgM1.29 g/L, IgA4.23 g/L, IgE 365.9 IU/mL
Lymphocyte subsets in peripheral blood	NK cells (9.3%), B cell (11.9%); CD4+ cells (43.2%), CD8+ cells (32.85%)	NK cells (4%), B cell (14%); CD4+ cells (39%), CD8+ cells (37%)	NK cells (11%), B cell (17%); CD4+ cells (33%), CD8+ cells (36%)
DHR test	No uptake in neutrophil oxidative burst after phorbolmyristate acetate stimulation	No uptake in neutrophil oxidative burst after phorbolmyristate acetate stimulation	No uptake in neutrophil oxidative burst after phorbolmyristate acetate stimulation
Gene mutation	NCF2 gene (compound heterozygosity mutation c.278 A > T and c.475delA)	NCF1 gene (homozygous mutation c.541delG)	NCF1 gene (homozygous mutation c.541delG)

CGD chronic granulomatous disease, DHR dihydrorhodamine-1,2,3, Igs immunoglobulins, NK natural killer