Table 1.
DAVID 6.7 (NIAID/NIH) enrichment analysis of synaptic and non-synaptic mitochondrial samples. Table comprises the top gene ontology (GO) terms associated with 1511 proteins identified in synaptic and non-synaptic mitochondrial samples. The analysis displays predominantly mitochondrial components, suggesting the samples are enriched for mitochondria
| Annotation | Enrichment Score 36.31 | Count | P_Value | Fold Change | Benjamini |
|---|---|---|---|---|---|
| GOTERM_CC_FAT | Mitochondrion | 231 | 2.50E-61 | 3.00E + 00 | 1.20E-58 |
| GOTERM_CC_FAT | Mitochondrial part | 138 | 4.50E-54 | 4.40E + 00 | 1.10E-51 |
| GOTERM_CC_FAT | Mitochondrial membrane | 109 | 1.70E-47 | 5.00E + 00 | 2.60E-45 |
| GOTERM_CC_FAT | Mitochondrial envelope | 111 | 4.20E-46 | 4.70E + 00 | 5.00E-44 |
| GOTERM_CC_FAT | Mitochondrial inner membrane | 93 | 7.40E-44 | 5.40E + 00 | 7.10E-42 |
| GOTERM_CC_FAT | Organelle inner membrane | 94 | 3.20E-42 | 5.20E + 00 | 2.50E-40 |
| GOTERM_CC_FAT | Organelle membrane | 164 | 4.80E-38 | 2.90E + 00 | 3.30E-36 |
| GOTERM_CC_FAT | Organelle envelope | 118 | 1.10E-35 | 3.60E + 00 | 6.50E.34 |
| GOTERM_CC_FAT | Envelope | 118 | 2.30E-35 | 3.50E + 00 | 1.20E-33 |
| KEGG_PATHWAY | Oxidative phosphorylation | 57 | 2.10E-31 | 6.20E + 00 | 3.00E-29 |
| SP_PIR_KEYWORDS | Mitochondrion | 104 | 6.80E-30 | 3.40E + 00 | 9.70E-28 |
| KEGG_PATHWAY | Parkinson’s disease | 54 | 2.10E-27 | 5.70E + 00 | 1.50E-25 |
| KEGG_PATHWAY | Huntington’s disease | 59 | 1.00E-24 | 4.70E + 00 | 4.90E-23 |
| KEGG_PATHWAY | Alzheimer’s disease | 58 | 5.40E-23 | 4.40E + 00 | 1.90E-21 |
| SP_PIR_KEYWORDS | Mitochondrial inner membrane | 35 | 6.40E-15 | 4.80E + 00 | 2.70E-13 |