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. 2017 Oct 27;12:77. doi: 10.1186/s13024-017-0221-9

Table 1.

DAVID 6.7 (NIAID/NIH) enrichment analysis of synaptic and non-synaptic mitochondrial samples. Table comprises the top gene ontology (GO) terms associated with 1511 proteins identified in synaptic and non-synaptic mitochondrial samples. The analysis displays predominantly mitochondrial components, suggesting the samples are enriched for mitochondria

Annotation Enrichment Score 36.31 Count P_Value Fold Change Benjamini
GOTERM_CC_FAT Mitochondrion 231 2.50E-61 3.00E + 00 1.20E-58
GOTERM_CC_FAT Mitochondrial part 138 4.50E-54 4.40E + 00 1.10E-51
GOTERM_CC_FAT Mitochondrial membrane 109 1.70E-47 5.00E + 00 2.60E-45
GOTERM_CC_FAT Mitochondrial envelope 111 4.20E-46 4.70E + 00 5.00E-44
GOTERM_CC_FAT Mitochondrial inner membrane 93 7.40E-44 5.40E + 00 7.10E-42
GOTERM_CC_FAT Organelle inner membrane 94 3.20E-42 5.20E + 00 2.50E-40
GOTERM_CC_FAT Organelle membrane 164 4.80E-38 2.90E + 00 3.30E-36
GOTERM_CC_FAT Organelle envelope 118 1.10E-35 3.60E + 00 6.50E.34
GOTERM_CC_FAT Envelope 118 2.30E-35 3.50E + 00 1.20E-33
KEGG_PATHWAY Oxidative phosphorylation 57 2.10E-31 6.20E + 00 3.00E-29
SP_PIR_KEYWORDS Mitochondrion 104 6.80E-30 3.40E + 00 9.70E-28
KEGG_PATHWAY Parkinson’s disease 54 2.10E-27 5.70E + 00 1.50E-25
KEGG_PATHWAY Huntington’s disease 59 1.00E-24 4.70E + 00 4.90E-23
KEGG_PATHWAY Alzheimer’s disease 58 5.40E-23 4.40E + 00 1.90E-21
SP_PIR_KEYWORDS Mitochondrial inner membrane 35 6.40E-15 4.80E + 00 2.70E-13