Table 8.
Cut‐point analysis using the optimized five‐site protocol to identify low lean tissue mass
| Variable median (IQR) | Low‐risk group (≤ −2.071) | Moderate‐risk group (−2.070 to −0.6040) | High‐risk group (≥ −0.6039) |
|---|---|---|---|
| Proportion of total cohort, n/N | 57/96 (59%) | 24/96 (25%) | 15/96 (16%) |
| Proportion of individuals categorized as low lean tissue by DXA, n/N | 1/57 (2%) | 6/24 (25%) | 10/15 (67%) |
| Age, years | 33.0 (24.0–69.5)c | 28.0 (22.0–69.0)c | 77.0 (63.0–80.0)a , b |
| Echogenicity, A.U. | 33.5 (29.8–36.9)c | 38.8 (31.0–43.6)c | 47.4 (40.4–55.6)a , b |
| Men | |||
| Four‐site thickness, cm | 4.34 (3.57–5.02)c | 4.14 (3.62–4.34) | 2.66 (2.22–2.79)a |
| Anterior upper arm thickness, cm | 3.64 (3.41–3.92)c | 3.21 (3.14–3.50) | 2.68 (2.24–2.80)a |
| Women | |||
| Four‐site thickness, cm | 3.70 (3.27–4.04)b , c | 2.98 (2.55–3.92)a , c | 2.30 (1.91–2.47)a , b |
| Anterior upper arm thickness, cm | 2.70 (2.47–2.93)b , c | 2.28 (2.16–2.36)a | 2.17 (1.94–2.30)a |
Log odds: −2.071, sensitivity = 0.9411; specificity = 0.7011, positive likelihood ratio = 3.23, negative likelihood ratio = 0.083. Log odds: −0.6039, sensitivity = 0.5882; specificity = 0.9367, positive likelihood ratio = 9.30, negative likelihood ratio = 0.44. A.U., arbitrary unit; DXA, dual‐energy X‐ray absorptiometry; IQR, interquartile range.
a
Significant difference from low‐risk group.
b
Significant difference from moderate‐risk group.
c
Significant difference from high‐risk group.