Table 1.

Renal function, body weight, and muscle weight profile for sham, 5/6‐nephrectomized (CKD) and AST‐120, L‐carnitine, or teneligliptin‐treated CKD mice

		CKD
	Sham	Control	AST‐120	Carnitine	Teneligliptin
BUN (mg/dL)	21.1 ± 1.2	56.7 ± 9.4b	45.5 ± 6.0a	53.9 ± 9.4b	66.9 ± 12.8b
SCr (mg/dL)	0.2 ± 0.02	0.8 ± 0.31a	0.4 ± 0.13	1.4 ± 0.42a	1.0 ± 0.05b
Final BW (g) (at 28 weeks)	49.1 ± 2.7	39.3 ± 1.4a	44.2 ± 0.5	45.4 ± 1.4	43.4 ± 0.9
Tibialis anterior (mg)	74.6 ± 3.3	70.0 ± 2.6	71.5 ± 1.7	74.0 ± 2.7	75.0 ± 3.7
Soleus (mg)	12.5 ± 0.6	10.3 ± 0.3a	10.7 ± 0.6	11.5 ± 0.5	11.3 ± 0.4
Gastrocnemius (mg)	216.0 ± 6.6	188.9 ± 9.1a	212.0 ± 5.5	211.0 ± 6.2	207.6 ± 6.2

Data are expressed as the mean ± standard error of the mean.

^a p < 0.05.

^b p < 0.01 compared with sham.

CKD, chronic kidney disease; BUN, blood urea nitrogen; SCr, serum creatinine; BW, body weight.