Table 1. Trans–cis ratios of compound 2, 3 and 4 before and after λ = 365 nm light irradiation in DMSOd6 at room temperature and half-lives of the cis-isomer at 30 °C and 37 °C in water.
Compound | 2 | 3 | 4 |
No irradiation (DMSOd6, trans–cis) | 97 : 3 | 97 : 3 | 97 : 3 |
365 nm light irradiation (DMSOd6, trans–cis) | 38 : 62 | 10 : 90 | 4 : 96 |
Half-life in H2O at 30 °C (hours) | >10 | 6.8 | 8.9 |
Half-life in H2O at 37 °C (hours) | >10 | 2.5 | 5.8 |