Table 1.

Molecular characteristics of type 1 and 2 ovarian cancer neoplasms.

	Histology	Molecular characteristic
Type 2	High grade serous	TP53 mutation BRCA1/2 HRD WT1 KRAS mutation PIK3CA amplification
	High grade endometrioid	PIK3CA mutation TP53 mutation WT1
Type 1	Low grade serous	KRAS mutation BRAF mutation ER+/PR+ EGFR amplification PIK3CA amplification/mutation PTEN mutation
	Low grade endometrioid	CTTNB1 mutation PTEN mutation PIK3CA mutation ARID1A mutation BRAF mutation
	Clear cell	IL6/JAK2/STAT3 pathway ARID1A mutation PTEN mutation or LOH PIK3CA amplification/mutation EGFR amplification /mutation
	Mucinous	KRAS mutation BRAF mutation HER2 amplification