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. 2017 Oct 20;13:1455–1461. doi: 10.2147/TCRM.S144437

Table 3.

Criteria to establish CRP and WBC as mediators in the association between serum vitamin D and ventricular dysfunction

Criteria results OR CI 95%
WBC
Vitamin D deficiency is significantly associated with WBC 2.1 (1.22–4.38)*
WBC is significantly associated with ventricular Ejection fraction 1.7 (1.42–5.21)*
Vitamin D deficiency is significantly associated with Ventricular ejection fraction 2.45 (1.25–4.32)*
The effect of serum vitamin D on the odds of developing Ventricular dysfunction is attenuated when WBC is added to the model 1.7 (1.43–6.21)
CRP
Vitamin D deficiency is significantly associated with CRP 1.36 (0.96–5.34)
CRP is significantly associated with ventricular Ejection fraction 2.65 (0.77–7.54)
Vitamin D deficiency is significantly associated with Ventricular ejection fraction 2.45 (1.25–4.32)*
The effect of serum vitamin D on the odds of developing Ventricular dysfunction is attenuated when CRP is added to the model 1.2 (0.55–5.99)

Note:

*

P<0.05.

Abbreviations: CRP, C-reactive protein; WBC, white blood cell.