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. 2017 Oct 20;12:7737–7750. doi: 10.2147/IJN.S148845

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© 2017 Ai et al. This work is published and licensed by Dove Medical Press Limited

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Micro-CT analysis of at the UHMWPE group, the UHMWPE–SF group, and the UHMWPE–SF/VEGF group at the time of 12 weeks after surgery.

Notes: (A) Micro-CT scans of specimens from three groups at the time of 12 weeks after surgery. The cross-sectional areas of the bone tunnels at the depth of 5 mm from the femur joint surface and tibial joint surface were measured. Representative axial micro-CT images: the upper and lower panels show images obtained from femur and tibia, respectively. Areas within the red dotted circles represent the cross-sectional areas that were measured for each bone tunnel. (B) Quantification of cross-sectional areas of the bone tunnels. (C) The trabecular bone volume fraction of the total tissue volume of interest (BV/TV) value. ^*P<0.05; ^**P<0.01.

Abbreviations: micro-CT, microcomputed tomography; SF, silk fibroin; UHMWPE, ultra-high-molecular-weight polyethylene; VEGF, vascular endothelial growth factor.