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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Pharmacogenet Genomics. 2017 Nov;27(11):402–409. doi: 10.1097/FPC.0000000000000311

Figure 2. Endoxifen Concentration by CYP2C8, CYP2C9, and CYP2C19 Activity.

Figure 2

Box and whisker plot (circles represent outliers) of steady-state endoxifen concentration stratified by predicted activity phenotype for CYP2C8 (left), CYP2C9 (middle), and CYP2C19 (right). Endoxifen concentration increased as predicted phenotypic activity increased for each gene (p=0.02, p=0.04, p=0.11, respectively).