Table 3.

Comparison of BMI and of metabolic parameters according to theTNF-α genotypes

	Total subjects
	GG	GA + AA	p-value
	(n. = 145)	(n = 49)
Age (yrs)	48.9 ± 1.3	49.4 ± 1.8	NS
Body Mass Index (kg/m2)	31.6 ± 0.6	29.1 ± 0.7	<0.05*
Blood glucose (mmol/L)	5.06 ± 01	4.79 ± 0.2	NS
Fasting plasma insulin (μU/ml)	18.9 ± 1.5	21.4 ± 3.8	NS
HOMA IIR	4.34 ± 0.3	4.79 ± 0.2	NS
Plasma lipids (mmol/L)
Total cholesterol	219.0 ± 4.4	214.4 ± 6.8	NS
Total triglycerides	154.2 ± 11.4	156.1 ± 15.6	NS
HDL cholesterol	48.5 ± 1.4	47.2 ± 2.8	NS
LDL cholesterol	132.5 ± 4.1	127.3 ± 7.1	NS

Data are given as means ± SEM. All p-values were corrected for differences in age GG, GA, and AA = TNF-α genotypes. ^* p-value after correction = not significant. The statistical analysis of total triglycerides and plasma insulin were performed on log-trasformed values, but the untrasformed values are given in table. Continuous variables were compared by t-test and categorical variables by Χ² test.