Table 1.
Elamipretide (N=6) |
Placebo (N=8) |
P value | |
---|---|---|---|
Gender (%Men)* | 3 (50%) | 4 (50%) | 0.99 |
Age (years) | 66.7 ± 6.8 | 72.5 ± 8.1 | 0.17 |
Creatinine (mg/dl) | 1.58 ± 0.36 | 1.83 ± 0.52 | 0.32 |
Iothalamate clearance (mL/min) | 46.8 ± 24.5 | 43.6 ± 12.3 | 0.99 |
Statins (yes/no) (%)* | 5/1 (83%) | 5/3 (63%) | 0.58 |
Number of anti-HTN drugs# | 3.5 (2, 5) | 4 (2, 6) | 0.44 |
SBP(mmHg) | 154.2 ±16.3 | 155.2 ± 19.5 | 0.92 |
DBP (mmHg) | 79.2 ± 9.1 | 72.5 ± 15.4 | 0.33 |
Weight (kg) | 90.7 ± 35.3 | 83.8 ± 14.6 | 0.66 |
BMI (kg/m2) | 33 ± 12.5 | 29.4 ± 3.9 | 0.51 |
Hematocrit % | 37.3 ± 2.6 | 36.2 ± 2.5 | 0.42 |
Mean±SD, GFR=glomerular filtration rate, Anti-HTN=antihypertensive, SBP=systolic blood pressure, DBP=diastolic blood pressure, ARAS= atherosclerotic Renal artery stenosis, N= number of patients.
Median (range) reported due to skewed data, P value obtained from Wilcoxon rank sum test,
Fisher’s exact test.