Table 3.

Multidetector CT Measurements of individual kidney volume, tissue perfusion, blood flow and iothalamate filtration of SK

Single Kidney- SK	Elamipretide (N=10)		Placebo (N=11)
	Baseline	3 months	baseline	3 months
Total kidney volume (CT), mL	124.7 ± 50	127.8 ± 54	115.6 ± 46.7	112.5 ± 46.9
Cortical volume, mL	71.6 ± 30.3	76 ± 32	68.8 ± 30.6	71.3 ± 30.6
Medullary volume, mL	53.1 ± 22	51.8 ± 23	46.8 ± 17.4	41.2 ± 17.5
Cortical perfusion, mL/min per mL of tissue	1.99 ± 0.8	2.9 ± 1.04*	2.6 ± 0.9	2.4 ± 0.39
Medullary perfusion, mL/min per mL of tissue	0.75 ± 0.37	0.95 ± 0.4	0.92 ± 0.4	0.89 ± 0.2
Total renal blood flow, mL/min	202 ± 129	261.7 ± 115*	234 ± 133	234 ± 99
Cortical flow, mL/min	157 ± 99	212 ± 93.1*	189 ± 111	194.9 ± 87
Medullary flow, mL/min	44.6 ± 36.9	49.7 ± 35	45.1 ± 27.7	39 ± 15

^*P<0.05 vs. baseline (paired t test and Wilcoxon signed-rank test).