Table 1.
Expression of Hepatic Lipid Metabolism Genes
| HFHS | 10,12 CLA | HFHS + Rosi | 10,12 CLA + Rosi | |
|---|---|---|---|---|
| Glucose metabolism | ||||
| Gck | 1.00 ± 0.06 | 1.07 ± 0.08 | 0.99 ± 0.05 | 0.84 ± 0.13 |
| Pk | 1.00 ± 0.08 | 0.99 ± 0.11 | 0.81 ± 0.06 | 0.80 ± 0.07 |
| Pck | 1.00 ± 0.15 | 1.24 ± 0.26 | 0.77 ± 0.07 | 0.84 ± 0.26 |
| Lipid metabolism | ||||
| Fasn | 1.00 ± 0.17 | 1.22 ± 0.25 | 0.94 ± 0.09 | 0.74 ± 0.12 |
| Acc | 1.00 ± 0.09 | 1.25 ± 0.11 | 1.16 ± 0.10 | 0.91 ± 0.13 |
| Srebp1c | 1.00 ± 0.06 | 0.88 ± 0.09 | 0.93 ± 0.08 | 0.91 ± 0.08 |
| Dgat1 | 1.00 ± 0.14 | 0.81 ± 0.19 | 0.94 ± 0.15 | 0.90 ± 0.14 |
| Cpt1a | 1.00 ± 0.08 | 0.82 ± 0.05 | 0.94 ± 0.04 | 0.93 ± 0.07 |
| Ppara | 1.00 ± 0.06 | 0.85 ± 0.05 | 0.95 ± 0.06 | 0.90 ± 0.06 |
| Pparg | 1.00 ± 0.09 | 0.73 ± 0.06 | 0.99 ± 0.06 | 0.83 ± 0.04 |
Abbreviations: Acc, acetyl coenzyme-A carboxylase; Cpt1a, carnitine palmitoyltransferase 1 α; Fasn, fatty acid synthase; Dgat1, diglyceride acyltransferase 1; Gck, glucokinase; Pck, phosphoenolpyruvate carboxykinase; Pk, pyruvate kinase; Ppara, peroxisome proliferator-activated receptor α; Srebp1c, sterol regulatory element binding protein 1c.