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. 2017 Jul 20;158(10):3212–3234. doi: 10.1210/en.2017-00468

Figure 2.

Figure 2.

Defining functionally active binding sites using sNR DBD mutant mouse models. (a–e) The proportion of ChIP-seq peaks that contain a 0- to 3-nt variant ERE (and remaining peaks) from five mouse uterine ChIP-seq datasets at L4 to L20 peak selection criteria: WT-E2-1hr, Uterus-ER, KIKO-E2, EAAE-E2, and Uterus-PGR-P4. (f–j) The proportion of ChIP-seq peaks that contain a 0- to 3-nt variant HRE (and remaining peaks) from five mouse uterine ChIP-seq datasets at L4 to L20 peak selection criteria: WT-E2-1hr, Uterus-ER, KIKO-E2, EAAE-E2, and Uterus-PGR-P4. (k–o) The proportion of ChIP-seq peaks that contain a 0- to 3-nt variant HRE (and remaining peaks) from four mouse liver ChIP-seq datasets at L4 to L20 peak selection criteria: GR-WT-pred-1, GR-WT-pred-2, GR-Dim-pred-1, and GR-Dim-pred-2. See also Supplemental Tables 2:1, 2:2 (2.8MB, xlsx) , and 2:5 (857.8KB, xlsx) .