Table 2.
Summary of the effect of viral infection or Poly(I:C) on human FM responses to LPS.
| Effect on LPS response |
Synergistic increase |
Additive increase |
Suppression | None |
|---|---|---|---|---|
| IL-1β | MHV-68 HSV-2 Poly(I:C) | |||
| IL-6 | MHV-68 Poly(I:C) | HSV-2 | ||
| IL-8 | MHV-68 | HSV-2 Poly(I:C) | ||
| IL-10 | MHV-68 HSV-2 Poly(I:C) | |||
| IL-12 | MHV-68 HSV-2 Poly(I:C) | |||
| IL-17 | MHV-68 HSV-2 Poly(I:C) | |||
| G-CSF | HSV-2 | MHV-68 Poly(I:C) | ||
| GM-CSF | Poly(I:C) | MHV-68 HSV-2 | ||
| IFNγ | MHV-68 HSV-2 Poly(I:C) | |||
| MCP-1 | MHV-68 HSV-2 | Poly(I:C) | ||
| MIP-1α | HSV-2 Poly(I:C) | MHV-68 | ||
| MIP-1β | MHV-68 HSV-2 Poly(I:C) | |||
| RANTES | Poly(I:C) | MHV-68 HSV-2 | ||
| TNFα | MHV-68 Poly(I:C) | HSV-2 | ||
| VEGF | Poly(I:C) | MHV-68 HSV-2 | ||
| GRO-α | HSV-2 | MHV-68 Poly(I:C) | ||
| IP10 | Poly(I:C) | MHV-68 | HSV-2 |