Table 2.
Difference in systolic and diastolic blood pressures between the high, medium, and low sodium diets according to DASH or control assignment
| Diet Control | Week
|
Mean Weekly Change (95% CI) | P-trend | P-interaction for difference in trends | |||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | ||||
| SBP | |||||||
| High | 132.8 (14.3) | 132.1 (12.5) | 132.1 (13.1) | 132.7 (11.9) | −0.04 (−0.48, 0.39) | 0.85 | Ref |
| Medium | 131.4 (12.7) | 131.0 (14.2) | 129.0 (13.2) | 130.0 (11.7) | −0.56 (−0.92, −0.20) | 0.002 | 0.08 |
| Low | 128.8 (12.3) | 127.7 (12.4) | 126.6 (11.4) | 126.0 (10.0) | −0.94 (−1.34, −0.55) | <0.001 | <0.001 |
| High vs Med | −1.38 (−4.05, 1.29) | −1.08 (−3.75, 1.58) | −3.15 (−5.78, −0.51) | −2.66 (−5.00, −0.32) | |||
| P | 0.31 | 0.43 | 0.02 | 0.03 | |||
| High vs Low | −4.03 (−6.66, −1.39) | −4.41 (−6.88, −1.93) | −5.51 (−7.97, −3.05) | −6.66 (−8.84, −4.47) | |||
| P | 0.003 | 0.0005 | <0.001 | <0.001 | |||
| DBP | |||||||
| High | 82.9 (8.7) | 83.2 (7.8) | 82.5 (7.9) | 83.2 (6.9) | 0.06 (−0.23, 0.35) | 0.68 | Ref |
| Medium | 83.3 (8.2) | 82.9 (8.7) | 81.0 (7.9) | 82.0 (6.4) | −0.56 (−0.89, −0.23) | 0.001 | 0.004 |
| Low | 82.1 (8.4) | 80.8 (7.6) | 80.4 (7.6) | 79.8 (6.0) | −0.70 (−0.99, −0.40) | <0.001 | <0.001 |
| High vs Med | 0.43 (−1.24, 2.10) | −0.37 (−2.02, 1.27) | −1.47 (−3.06, 0.11) | −1.24 (−2.57, 0.09) | |||
| P | 0.61 | 0.65 | 0.07 | 0.07 | |||
| High vs Low | −0.80 (−2.50, 0.89) | −2.40 (−3.93, −0.86) | −2.07 (−3.63, −0.52) | −3.43 (−4.72, −2.13) | |||
| P | 0.35 | 0.002 | 0.009 | <0.001 | |||
| DASH | |||||||
| SBP | |||||||
| High | 128.4 (12.9) | 127.9 (13.2) | 127.0 (12.6) | 126.7 (11.2) | −0.60 (−1.00, −0.20) | 0.003 | Ref |
| Medium | 126.4 (13.0) | 125.8 (13.3) | 124.0 (11.9) | 125.1 (11.4) | −0.59 (−1.01, −0.17) | 0.006 | 0.92 |
| Low | 125.0 (12.8) | 122.8 (12.2) | 123.4 (12.8) | 123.5 (10.4) | −0.42 (−0.86, 0.02) | 0.06 | 0.56 |
| High vs Med | −1.94 (−4.50, 0.62) | −2.10 (−4.70, 0.51) | −3.02 (−5.44, −0.60) | −1.56 (−3.77, 0.65) | |||
| P | 0.14 | 0.11 | 0.01 | 0.17 | |||
| High vs Low | −3.35 (−5.88, −0.82) | −5.05 (−7.55, −2.54) | −3.61 (−6.13, −1.08) | −3.20 (−5.31, −1.09) | |||
| P | 0.01 | 0.0001 | 0.005 | 0.003 | |||
| DBP | |||||||
| High | 81.2 ( 9.2) | 81.4 ( 8.4) | 81.3 ( 8.5) | 80.8 ( 6.8) | −0.16 (−0.50, 0.17) | 0.34 | Ref |
| Medium | 80.8 (8.4) | 80.8 (8.2) | 79.8 (8.3) | 80.3 (7.2) | −0.30 (−0.59, −0.01) | 0.05 | 0.59 |
| Low | 81.0 ( 7.8) | 79.8 ( 8.3) | 79.8 ( 8.2) | 79.2 ( 6.3) | −0.54 (−0.82, −0.25) | <0.001 | 0.10 |
| High vs Med | −0.40 (−2.14, 1.35) | −0.67 (−2.30, 0.96) | −1.55 (−3.21, 0.10) | −0.54 (−1.91, 0.83) | |||
| P | 0.65 | 0.42 | 0.07 | 0.44 | |||
| High vs Low | −0.25 (−1.93, 1.42) | −1.65 (−3.29, −0.01) | −1.52 (−3.18, 0.14) | −1.60 (−2.88, −0.31) | |||
| P | 0.76 | 0.05 | 0.07 | 0.01 | |||