Table 3.
Difference in systolic and diastolic blood pressures between the high and low sodium diets overall and by diet in participants who were hypertensive at baseline
| Diet Control | Week
|
Mean Weekly Change (95% CI) | P-trend | P-interaction for difference in trends | |||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | ||||
| SBP | |||||||
| High | 141.0 (13.8) | 139.9 (12.2) | 139.7 (14.0) | 140.9 (10.9) | −0.07 (−0.75, 0.61) | 0.84 | Ref |
| Medium | 139.0 (13.0) | 140.6 (14.4) | 137.5 (13.7) | 138.5 (12.0) | −0.36 (−0.96, 0.23) | 0.23 | 0.45 |
| Low | 136.5 (11.8) | 134.7 (13.1) | 132.3 (12.3) | 132.5 (10.8) | −1.45 (−2.13, −0.77) | <0.001 | 0.005 |
| High vs Med | −2.01 (−6.18, 2.16) | 0.65 (−3.52, 4.82) | −2.16 (−6.57, 2.26) | −2.40 (−6.01, 1.22) | |||
| P | 0.34 | 0.76 | 0.34 | 0.19 | |||
| High vs Low | −4.55 (−8.57, −0.52) | −5.24 (−9.22, −1.26) | −7.35 (−11.55, −3.15) | −8.43 (−11.85, −5.00) | |||
| P | 0.03 | 0.01 | 0.0007 | <0.001 | |||
| DBP | |||||||
| High | 85.5 ( 9.0) | 85.1 ( 8.7) | 85.5 ( 7.8) | 86.1 ( 6.8) | 0.24 (−0.25, 0.73) | 0.34 | Ref |
| Medium | 85.8 (8.2) | 86.1 (8.5) | 83.0 (8.5) | 84.5 (6.6) | −0.64 (−1.18, −0.10) | 0.02 | 0.007 |
| Low | 84.2 ( 8.9) | 82.4 ( 8.1) | 81.5 ( 8.5) | 81.6 ( 5.9) | −0.85 (−1.31, −0.38) | <0.001 | 0.001 |
| High vs Med | 0.27 (−2.42, 2.95) | 1.06 (−1.63, 3.75) | −2.47 (−5.07, 0.14) | −1.66 (−3.76, 0.45) | |||
| P | 0.84 | 0.44 | 0.06 | 0.12 | |||
| High vs Low | −1.29 (−4.09, 1.52) | −2.63 (−5.27, 0.02) | −4.00 (−6.59, −1.41) | −4.57 (−6.58, −2.56) | |||
| P | 0.37 | 0.05 | 0.003 | 0 | |||
| DASH | |||||||
| SBP | |||||||
| High | 135.3 (13.6) | 135.0 (13.3) | 133.0 (12.9) | 133.9 (10.6) | −0.61 (−1.36, 0.14) | 0.11 | Ref |
| Medium | 133.0 (14.1) | 133.9 (14.2) | 131.1 (11.9) | 131.9 (11.6) | −0.60 (−1.34, 0.13) | 0.11 | 0.94 |
| Low | 132.8 (13.6) | 128.8 (12.5) | 130.0 (13.4) | 128.7 (10.4) | −1.16 (−2.00, −0.33) | 0.006 | 0.37 |
| High vs Med | −2.32 (−6.67, 2.03) | −1.10 (−5.39, 3.20) | −1.90 (−5.80, 1.99) | −2.04 (−5.51, 1.43) | |||
| P | 0.2932 | 0.6154 | 0.3361 | 0.2482 | |||
| High vs Low | −2.53 (−6.75, 1.69) | −6.18 (−10.18, −2.18) | −3.00 (−7.10, 1.10) | −5.17 (−8.43, −1.91) | |||
| P | 0.24 | 0.0027 | 0.151 | 0.0021 | |||
| DBP | |||||||
| High | 84.0 ( 8.8) | 84.5 ( 7.6) | 84.6 ( 8.2) | 83.8 ( 6.5) | −0.10 (−0.64, 0.45) | 0.72 | Ref |
| Medium | 83.7 (8.5) | 83.8 (8.8) | 83.0 (8.6) | 83.4 (6.8) | −0.17 (−0.64, 0.31) | 0.49 | 0.92 |
| Low | 83.9 ( 7.9) | 82.6 ( 8.2) | 81.8 ( 8.4) | 81.4 ( 6.2) | −0.89 (−1.36, −0.42) | <0.001 | 0.03 |
| High vs Med | −0.31 (−3.02, 2.39) | −0.75 (−3.32, 1.82) | −1.58 (−4.22, 1.05) | −0.42 (−2.51, 1.67) | |||
| P | 0.82 | 0.56 | 0.24 | 0.69 | |||
| High vs Low | −0.12 (−2.70, 2.47) | −1.92 (−4.36, 0.53) | −2.81 (−5.41, −0.20) | −2.45 (−4.43, −0.47) | |||
| P | 0.93 | 0.12 | 0.03 | 0.02 | |||