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. Author manuscript; available in PMC: 2019 Jan 30.
Published in final edited form as: Behav Brain Res. 2017 Sep 18;337:34–45. doi: 10.1016/j.bbr.2017.09.026

Figure 1. General phenotype of HdhQ350/+ male and female mice compared to wild-type littermates.

Figure 1

(A) Male and (B) female HdhQ350/+ mice showed reduced weight compared to their respective wild-type littermates. (C) When normalized to their respective wild-type littermates, both male and female HdhQ350/+ had similar reductions in weight. (D) Male and (E) female HdhQ350/+ mice showed reduced grip strength, starting at 30 weeks of age. (F) When normalized to their respective wild-type littermates, both sexes had similar reductions in grip strength. N=7–8 for all groups. Error bars represent S.E.M. and *p<0.05, **p<0.01, ***p<0.001 with two-way ANOVA with Bonferroni post-hoc test.