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. Author manuscript; available in PMC: 2019 Jan 30.
Published in final edited form as: Behav Brain Res. 2017 Sep 18;337:34–45. doi: 10.1016/j.bbr.2017.09.026

Figure 6. Psychiatric and cognitive functions are unaffected in HdhQ350/+ males and females.

Figure 6

On the elevated plus maze, HdhQ350/+ (A) males and (B) females generally spent similar amounts of time in the closed arms than their respective wild-type littermates. HdhQ350/+ (C) males and (D) females spent similar amounts of time in the open arms than their respective wild-type littermates. Exploration was measured by the distance mice traveled within the first hour of being placed into the PhenoTyper chamber. (E) Male HdhQ350/+ mice and (F) female HdhQ350/+ mice covered similar distances than their respective wild-type littermates at 40 and 60 weeks of age. N=7–8 for all groups. Error bars represent S.E.M., with two-way ANOVA with Bonferroni post-hoc test.