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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Cancer Genet. 2017 Aug 17;216-217:111–119. doi: 10.1016/j.cancergen.2017.08.001

Table 1.

Clinical Characteristics

Characteristic n (%)
Study Participants
Previous pathogenic or likely pathogenic clinical testing 8
Sequenced 43
Total analyzed in study 51

Gender
Female 33 (55)
Male 18 (35)

Mean age at gastric cancer diagnosis, years 46.9 years (range 17–85)

Racial and Ethnic Categories*
White (Non-Hispanic Caucasian) 25 (49)
Hispanic or Latino 16 (31)
Asian 8 (16)
Black or African-American 1 (2)
American Indian 1 (2)

Family history
First-degree relative (FDR) with gastric cancer 19 (37)
More than one FDR with gastric cancer 9 (18)
FDR and second degree relative (SDR) with gastric cancer 7 (14)
FDR and/or SDR with gastric cancer 26 (51)
FDR and/or SDR with one or more of the following cancers: Breast, colorectal, thyroid, uterine, leukemia, gastric, pancreatic, or ovarian 45 (88)

Histology
Adenocarcinoma, Diffuse type 23 (45)
Adenocarcinoma, Intestinal type 9 (18)
Adenocarcinoma, not specified or only noted as indeterminate/poorly differentiated 4 (8)
Gastrointestinal Stromal Tumor 2 (4)
Unknown (presumed adenocarcinoma) 13 (25)

Participants with other solid tumor primary cancers 17 (33)
Breast 7 (14)
Colorectal 3 (6)
Sarcoma 2 (4)
Ovarian, prostate, or uterine, carcinoid, or bladder 5 (10)