Table 1.
Clinical Characteristics
| Characteristic | n (%) | |
|---|---|---|
| Study Participants | ||
| Previous pathogenic or likely pathogenic clinical testing | 8 | |
| Sequenced | 43 | |
| Total analyzed in study | 51 | |
|
| ||
| Gender | ||
| Female | 33 (55) | |
| Male | 18 (35) | |
|
| ||
| Mean age at gastric cancer diagnosis, years | 46.9 years (range 17–85) | |
|
| ||
| Racial and Ethnic Categories* | ||
| White (Non-Hispanic Caucasian) | 25 (49) | |
| Hispanic or Latino | 16 (31) | |
| Asian | 8 (16) | |
| Black or African-American | 1 (2) | |
| American Indian | 1 (2) | |
|
| ||
| Family history | ||
| First-degree relative (FDR) with gastric cancer | 19 (37) | |
| More than one FDR with gastric cancer | 9 (18) | |
| FDR and second degree relative (SDR) with gastric cancer | 7 (14) | |
| FDR and/or SDR with gastric cancer | 26 (51) | |
| FDR and/or SDR with one or more of the following cancers: Breast, colorectal, thyroid, uterine, leukemia, gastric, pancreatic, or ovarian | 45 (88) | |
|
| ||
| Histology | ||
| Adenocarcinoma, Diffuse type | 23 (45) | |
| Adenocarcinoma, Intestinal type | 9 (18) | |
| Adenocarcinoma, not specified or only noted as indeterminate/poorly differentiated | 4 (8) | |
| Gastrointestinal Stromal Tumor | 2 (4) | |
| Unknown (presumed adenocarcinoma) | 13 (25) | |
|
| ||
| Participants with other solid tumor primary cancers | 17 (33) | |
| Breast | 7 (14) | |
| Colorectal | 3 (6) | |
| Sarcoma | 2 (4) | |
| Ovarian, prostate, or uterine, carcinoid, or bladder | 5 (10) | |