Table 2.

Mean and Standard Deviations of FA in White Matter Parcellated ROIs Based on the FreeSurfer Atlas.

ROIs		MDD (N= 29)		HV (N= 16)		ANCOVA*
		Mean	SD	Mean	SD	F-score	p
cACC	Left	0.591	0.038	0.625	0.036	8.87	0.005
	Right	0.595	0.038	0.618	0.040	3.56	0.07
rACC	Left	0.558	0.032	0.579	0.036	3.82	0.06
	Right	0.583	0.038	0.598	0.036	1.93	0.17
LOFC	Left	0.444	0.022	0.455	0.024	2.67	0.11
	Right	0.443	0.022	0.448	0.020	0.73	0.39
MOFC	Left	0.433	0.027	0.448	0.028	3.48	0.07
	Right	0.449	0.027	0.470	0.024	7.58	0.009
dlPFC	Left	0.412	0.022	0.430	0.024	6.69	0.01
	Right	0.421	0.022	0.429	0.024	1.18	0.29
DMPFC	Left	0.484	0.016	0.498	0.016	6.48	0.02
	Right	0.478	0.022	0.490	0.020	3.72	0.06
Insula	Left	0.517	0.027	0.517	0.028	0.001	0.97
	Right	0.496	0.027	0.499	0.024	0.12	0.73

^*ANCOVA was performed for each ROI with age and sex as covariates for MDD and HV group comparisons (df= 1, 41).

Abbreviations: ANCOVA: univariate analysis of covariance, cACC= caudal anterior cingulate cortex, DMPFC= dorsomedial prefrontal cortex, dlPFC= dorsolateral prefrontal cortex, FA= fractional anisotropy, HV= healthy volunteer, MDD= major depressive disorder, LOFC= lateral orbitofrontal cortex, MOFC= medial orbitofrontal cortex, ROIs= regions-of-interest, rACC= rostral anterior cingulate cortex, SD= standard deviation.