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. 2017 Sep 16;74(23):4305–4314. doi: 10.1007/s00018-017-2649-z

Table 1.

Actions of periostin on lung epithelial cells and fibroblasts

Cell type Action References
Epithelial cells Enhanced wound repair in vitro [98]
Conflicting reports on migration [98, 99]
Enhanced proliferation [99]
Promotes epithelial to mesenchymal transition [100]
Increases collagen deposition and crosslinking of collagen fibers [100]
Enhanced mucin production (MUC5AC) [101]
Fibroblasts Increased proliferation [20]
Increased expression of collagen I and III genes [20]
Increased wound closure [20]

Adapted from Ref. [20]