TABLE 1.
Visit | DHEA | BRIEF Working Memory |
CANTAB Spatial Working Memory |
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# Scans per Visit # | 1 | n = 121 scans (F = 69) | n = 119 scans (F = 68) | n = 119 scans (F = 68) |
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2 | n = 110 scans (F = 71) | n = 91 scans (F = 57) | n = 97 scans (F = 62) | |
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3 | n = 93 scans (F = 50) | n = 35 scans (F = 21) | n = 41 scans (F = 25) | |
Total = 324 (F = 190) | Total = 245 (F = 146) | Total = 257 (F = 155) | ||
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# Participants per # Scans Completed | 1 scan | n =129 participants (F = 70) | n = 132 participants (F = 75) | n = 126 participants (F = 71) |
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2 scans | n = 66 participants (F = 39) | n = 52 participants (F = 31) | n = 55 participants (F = 33) | |
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3 scans | n = 21 participants (F = 14) | n = 3 participants (F = 3) | n = 7 participants (F = 6) | |
Total = 216 (F = 123) | Total = 187 (F = 109) | Total = 188 (F = 110) | ||
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Testosterone (ug/dL) | 1 | n = 121, mean = 99.20, SD = 74.14 | n = 119, mean = 99.12, SD = 74.76 | n = 119, mean = 98.65, SD = 74.53 |
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2 | n = 110, mean = 74.00, SD = 45.83 | n = 91, mean = 71.84, SD = 43.97 | n = 97, mean = 72.75, SD = 42.68 | |
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3 | n = 93, mean = 105.23, SD = 101.34 | n = 35, mean = 88.33, SD = 99.01 | n = 41, mean = 93.11, SD = 93.04 | |
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Estradiol (ug/dL) | 1 | n = 121, mean = 10.87, SD = 5.63 | n = 119, mean = 10.86, SD = 5.67 | n = 119, mean = 10.64, SD = 5.12 |
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2 | n = 110, mean = 12.11, SD = 6.19 | n = 91, mean = 12.42, SD = 6.16 | n = 97, mean = 12.60, SD = 6.13 | |
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3 | n = 93, mean = 16.82, SD = 10.01 | n = 35, mean = 19.45, SD = 10.93 | n = 41, mean = 19.68, SD = 10.27 | |
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DHEA (ug/dL) | 1 | n = 121, mean = 103.07, SD = 100.03 | n = 119, mean = 103.90, SD = 100.66 | n = 119, mean = 103.39, SD = 100.82 |
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2 | n = 110, mean = 188.84, SD = 171. 85 | n = 91, mean = 173.19, SD = 157.78 | n = 97, mean = 181.13, SD = 164.22 | |
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3 | n = 93, mean = 197.28, SD = 164.48 | n = 35, mean = 147.44, SD = 138.07 | n = 41, mean = 168.69, SD = 141.59 | |
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Season of sampling | 1 | Spring = 0 | Spring = 0 | Spring = 0 |
Summer = 11 | Summer = 11 | Summer = 10 | ||
Fall = 110 | Fall = 108 | Fall = 109 | ||
Winter= 0 | Winter = 0 | Winter = 0 | ||
Total = 121 | Total = 119 | Total = 119 | ||
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2 | Spring = 0 | Spring = 0 | Spring = 0 | |
Summer = 0 | Summer = 0 | Summer = 0 | ||
Fall = 108 | Fall = 89 | Fall = 95 | ||
Winter = 2 | Winter = 2 | Winter = 2 | ||
Total = 110 | Total = 91 | Total = 97 | ||
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3 | Spring = 0 | Spring = 0 | Spring = 0 | |
Summer = 0 | Summer = 0 | Summer = 0 | ||
Fall = 3 | Fall = 0 | Fall = 0 | ||
Winter = 90 | Winter = 35 | Winter = 41 | ||
Total = 93 | Total = 35 | Total = 41 | ||
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Collection time (min after midnight) | 1 | n = 121, mean = 682.58, SD = 139.42 | n = 119, mean = 684.90, SD = 139.43 | n = 119, mean = 682.52, SD = 139.31 |
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2 | n = 110, mean = 710.63, SD = 115.73 | n = 91, mean = 713.27, SD = 109.35 | n = 97, mean = 715.28, SD = 115.53 | |
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3 | n = 93, mean = 702.38, SD = 123.07 | n = 35, mean = 699.03, SD = 132.12 | n = 41, mean = 694.93, SD = 139.75 | |
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Age (years) | 1 | n = 121, mean = 12.71, SD = 3.22 | n = 119, mean = 12.63, SD = 3.19 | n = 119, mean = 12.69, SD = 3.21 |
Age range = 6.09 to 18.24 | Age range = 6.08 to 18.24 | Age range = 6.09 to 18.24 | ||
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2 | n = 110, mean = 13.48, SD = 3.66 | n = 91, mean = 12.80, SD = 3.31 | n = 97, mean = 13.29, SD = 3.64 | |
Age range = 6.79 to 20.17 | Age range = 6.79 to 18.90 | Age range = 6.79 to 20.05 | ||
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3 | n = 93, mean = 14.50, SD = 3.77 | n = 35, mean = 12.76, SD = 2.64 | n = 41, mean =14.15, SD = 3.95 | |
Age range = 9.08 to 22.26 | Age range = 9.07 to 17.91 | Age range = 9.07 to 22.26 | ||
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Sex F = female M = male | 1 | F = 69, M = 52 | F = 68, M = 51 | F = 68, M = 51 |
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2 | F = 71, M = 39 | F = 57, M = 34 | F = 62, M = 35 | |
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3 | F = 50, M = 43 | F = 21, M = 14 | F = 25, M = 16 | |
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Pubertal stage | 1 | n = 121, mean = 2.53 SD = 1.47 | n = 119, mean = 2.51 SD = 1.478 | n = 119, mean = 2.52, SD = 1.478 |
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2 | n = 110, mean = 2.52, SD = 1.48 | n = 91, mean = 2.46, SD = 1.463 | n = 97, mean = 2.42, SD = 1.45 | |
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3 | n = 93, mean = 3.05, SD = 1.492 | n = 35, mean = 3.03, SD = 1.445 | n = 41, mean = 2.95, SD = 1.465 | |
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Handedness | 1 | L = 8, R = 113 Total = 121 | L = 8, R = 111 Total = 119 | L = 8, R = 111 Total = 119 |
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2 | L = 9, R = 101 Total = 110 | L = 8, R = 83 Total = 91 | L = 7, R = 90 Total = 97 | |
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3 | L = 8, R = 85 Total = 93 | L = 3, R = 32 Total = 35 | L = 3, R = 38 Total = 41 | |
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Total brain volume (cm3) | 1 | n = 121, mean = 1270.55 SD = 123.26 | n = 119, mean = 1270.89, SD = 123.94 | n = 119, mean = 1273.23, SD = 122.19 |
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2 | n = 110, mean = 1268.22, SD = 126.26 | n = 91, mean = 1275.79, SD = 126.51 | n = 97, mean = 1273.20, SD = 125.64 | |
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3 | n = 93, mean = 1285.88, SD = 140.12 | n = 35, mean = 1286.54, SD = 139.63 | n = 41, mean = 1272.81, SD = 130.80 | |
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Left hippocampus (mm3) | 1 | n = 121, mean = 2954.43 SD = 322.78 | n = 119, mean = 2955.73, SD = 324.86 | n = 119, mean = 2961.26, SD = 320.13 |
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2 | n = 110, mean = 2971.405, SD = 296. 595 | n = 91, mean = 2964.77, SD = 304.25 | n = 97, mean = 2966.92, SD = 305.61 | |
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3 | n = 93, mean = 3071.97, SD = 356. 90 | n = 35, mean = 2992.22, SD = 354.68 | n = 41, mean = 2992.48, SD = 336.63 | |
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Right hippocampus (mm3) | 1 | n = 121, mean = 3045.01 SD = 349.12 | n = 119, mean = 3043.366, SD = 351,70 | n = 119, mean = 3048.76, SD = 349.36 |
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2 | n = 110, mean = 3064.97, SD = 330. 436 | n = 91, mean = 3064. 55, SD = 343.96 | n = 97, mean = 3059.62, SD = 343.18 | |
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3 | n = 93, mean = 3140.50, SD = 380. 25 | n = 35, mean = 3054.88, SD = 361.08 | n = 41, mean = 3059.113, SD = 339.81 |
Each column shows the characteristics of the sample used for each set of analyses (DHEA-related analyses, BRIEF and CANTAB analyses). The data are divided into 3 visits (as each child was followed longitudinally up to 3 times, every 2 years, for a total of 4 years), and the subdivisions ‘1, 2, and 3’ for each row represent each of these visits, except for the row ‘# Participants per # of Scans completed’, for which each row represents the number of scans completed. F=female; M=male