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. 2017 Oct 23;8:1346. doi: 10.3389/fimmu.2017.01346

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Copyright © 2017 Ichii, Kimura, Okamura, Horino, Nakamura, Sasaki, Elewa and Kon.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of IL-1 family members in unilateral ureter obstruction (UUO) kidneys. (A) Gene expression of IL-1 family members analyzed by microarray at day 7 after UUO. The values indicate the fold increase of UUO kidney to Cont kidney. Heatmap scale bars indicate the relative changes. (B) Time course of mRNA expression of IL-1 family members and Kim-1 in UUO kidneys (n = 1). (C) Relative mRNA expression of IL-1 family members and Kim-1 in Cont and UUO kidneys. Values = mean ± SE. A significant difference from the Cont is indicated by *(P < 0.05) or **(P < 0.01). A significant difference from 12 h in the same group is indicated by ^†(P < 0.05) or ^††(P < 0.01). q ≥ 4 kidneys. (D) Immunoblotting analysis of IL-36α and β-actin expression in Cont and UUO kidneys.