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. 2017 Oct 23;8:1346. doi: 10.3389/fimmu.2017.01346

Table 1.

Relationship between IL-36α expression and renal dysfunction in the folic acid (FA)-induced AKI model.

Indices FA-induced AKI model
Renal function
Blood urea nitrogen Serum creatinine (Cr) Urinary Cr
Kim-1 mRNA ρ 0.660 0.850 −0.660
P 0.018* 0.016* 0.020*
N 12 7 12
Il1f6 mRNA ρ 0.660 0.780 −0.830
P 0.020* 0.041* 0.01<**
N 12 7 12
IL-36α protein ρ 0.880 0.685 −0.710
P 0.01<** 0.090 0.010*
N 12 7 12

Male B6 mice at 10 weeks of age were analyzed after FA injection for 8 h. ρ, Spearman’s rank correlation coefficient.

*P < 0.05.

**P < 0.01.