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. 2017 Oct 27;8:1167. doi: 10.1038/s41467-017-00802-2

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.1

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Fig. 3 — SNP-Alcohol 30-Day Frequency interaction results. SNP-environment analysis was performed for 33,622 SNPs and 2044 samples (390 cases, 1654 controls) using logistic regression in PLATO. This Synthesis View⁵⁸ plot denotes the SNP (nearest gene) on the left and the track to the right displays the –log10 of the uncorrected LRT p value. The red line denotes the Bonferroni threshold for corrected significance (uncorrected LRT p: 1.49 × 10⁻⁶; α = 0.05, 33,622 tests)