Table 1.

Comparative organization of the three neurogenic niches the SVZ, SGZ, and the hypothalamic neurogenic niche (Hyp) in five mammalian species.

	SVZ					SGZ		Hyp
	PPCs	Hypocellular Gap	RMS	Migration rates	Neurogenic olfactory ventricle	PPCs	Adult born GCs	PPCs	DCX+ Neuroblasts	Adult born neurons
Rodents	++	0	+	3–7 days in mice	0	++	+	++	±	POMC, NPY, AgRP
				10–12 days in rats
Rabbit	++	+	+	ND	+	ND	ND	ND	ND	ND
NHP	++	+	+	2–3 months	0	++	+	ND	ND	ND
Sheep	++	+	+	1 month	+	+	+	++	++	NPY
Adult Human	+	0	0	ND	0	++	++	ND	ND	ND

NHP, Non-human primates; PPCs, proliferative progenitor cells; RMS, rostral migratory stream; ++, strong presence; +, presence; ±, weak presence; 0, absence; ND, Not determined. POMC, Pro-Opiomelanocortin. NPY, Neuropeptide Y; AgRP, Agouti related Peptide. Rodents, Lois and Alvarez-Buylla, 1994; Kokoeva et al., 2005; Pierce and Xu, 2010; Lee et al., 2012; Haan et al., 2013; Rabbits, Bonfanti and Ponti, 2008; Larriva-Sahd, 2014; NHP, Gil-Perotin et al., 2009; Sawamoto et al., 2011; Wang et al., 2011; Sheep, Migaud et al., 2011; Brus et al., 2013; Batailler et al., 2014. Adult human, Quinones-Hinojosa et al., 2006; Butz et al., 2008; Sanai et al., 2011; Spalding et al., 2013.