Table 3.

Multivariate Adjusted* Hazard Ratios for Coronary Heart Disease and Stroke Incidence, Cardiovascular Disease and All-cause Mortality According to Hypertension and Diabetes Status. Tehran Lipids and Glucose Study (1999–2014).

	CHD Incidence	P-value	Stroke Incidence	P-value	CVD Mortality	P-value	All-cause Mortality	P-value
Men
HTN+/DM−	Reference	—	Reference	—	Reference	—	Reference	—
HTN−/DM+	1.13(0.79–1.62)	0.5	1.08(0.57–2.04)	0.82	1.43(0.85–2.39)	0.18	1.72(1.2–2.45)	0.003
HTN+/DM+	1.67(1.19–2.34)	0.003	2.14(1.23–3.72)	0.007	3.21(2.03–5.06)	<0.001	2.61(1.83–3.71)	<0.001
HTN−/DM−	0.63(0.48–0.82)	0.001	0.29(0.16–0.52)	<0.001	0.34(0.21–0.56)	<0.001	0.48(0.35–0.66)	<0.001
Women
HTN+/DM−	Reference	—	Reference	—	Reference	—	Reference	—
HTN−/DM+	1.28(0.83–1.97)	0.26	1.07(0.4–2.86)	0.89	1.04(0.45–2.41)	0.92	1.28(0.73–2.26)	0.38
HTN+/DM+	2.31(1.69–3.15)	<0.001	1.28(0.67–2.42)	0.45	1.99(1.20–3.31)	0.008	2.09(1.45–3.01)	<0.001
HTN−/DM−	0.56(0.4–0.79)	0.001	0.85(0.45–1.61)	0.63	0.34(0.16–0.70)	0.004	0.77(0.51–1.16)	0.21
Total Population
HTN+/DM−	Reference	—	Reference	—	Reference	—	Reference	—
HTN−/DM+	1.19(0.9–1.57)	0.21	1.07(0.63–1.82)	0.8	1.28(0.83–1.97)	0.27	1.62(1.2–2.18)	0.001
HTN+/DM+	1.96(1.57–2.46)	<0.001	1.66(1.1–2.52)	0.017	2.6(1.85–3.65)	<0.001	2.32(1.8–2.98)	<0.001
HTN−/DM−	0.61(0.49–0.75)	<0.001	0.44(0.29–0.68)	<0.001	0.34(0.23–0.51)	<0.001	0.57(0.44–0.73)	<0.001

*Adjusted for sex (for total population), age, BMI, waist to hip ratio, education level, current smoking, low physical activity, and hypercholesterolemia.

CHD, coronary heart disease; CVD, cardiovascular disease; HTN, hypertension; DM, type 2 diabetes mellitus.

Standard errors were reported as confidence intervals and P-values.