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. 2017 Oct 27;7:14285. doi: 10.1038/s41598-017-14561-z

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Visualization of k-means clustering of differentially expressed probe sets with Euclidean distance measurement and k = 7 group clusters. Replicates are displayed in the vertical axis and genes in the horizontal axis. Log2 transformed signal intensities are depicted in colour code. The heatmap indicates high expression levels in red, intermediate expression level in dark grey and low expression levels in green. Representative diagrams for the gene expression pattern of the different clusters are shown on the right.