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. 2017 Oct 23;8:1390. doi: 10.3389/fimmu.2017.01390

Figure 4.

Figure 4

The enhanced accumulation of leukocyte subsets in the L3TU tumor-draining lymph node (TDLN) is negated by blocking CCL3, but enhanced by natural killer (NK) depletion. (A–C) Absolute numbers of immune cell subsets in the TDLN 5 days post-tumor injection of mice with and without the anti-CCL3 blocking Ab or NK cell (anti-Asialo-GM1) depletion Ab. N = 3 mice per cohort. NI (circles), WTTU (squares), and L3TU (triangles) cohorts were conducted concurrently along with the CCL3-blocking and NK depletion cohorts. IgG1a antibody was administered to WTTU, and L3TU cohorts as controls. Not significant (ns), p > 0.05; *p = 0.01–0.05; **p = 0.001–0.01; ***p = 0.0001–0.001; ****p < 0.0001.