Table 1.

Dock score of the top nine interacting drugs with multiple target proteins

Name of the ligand	Docking score
	AChE (4EY6)	BuChE (1P0M)	MAO A (2Z5X)	BACE 1 (3L5E)	BACE 1 (4D8C)	NMDA (1PBQ)
Positive control	Donepezil − 11.02	Rivastigmine − 3.123	Marplan − 8.354	LY2886721 − 6.123	LY2886721 − 6.80	Memantine − 4.029
Sulmepride	− 11.508	–	–	− 7.246	− 3.649	− 4.831
Promazine hydrochloride	− 11.074	–	− 7.978	− 5.907	− 6.784	− 4.711
Bromperidol	− 10.927	− 8.111	− 5.52	− 6.576	− 7.486	− 5.247
Anisopirol	− 11.001	− 7.977	− 5.26	− 6.083	− 8.169	− 6.903
Melperone	− 11.423	− 6.663	− 8.91	− 7.249	− 6.524	− 6.067
Pimozide	− 14.969	− 8.13	–	− 8.386	− 8.968	− 6.854
Benperidol	− 14.425	− 7.163	− 6.598	− 6.742	− 9.076	− 6.778
Azabuperone	− 11.882	− 7.938	− 5.861	− 7.584	− 4.167	− 6.51
Anisoperidone	–	− 7.989	− 6.324	− 8.513	− 7.11	− 5.196