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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: J Pain. 2017 Jun 29;18(11):1333–1345. doi: 10.1016/j.jpain.2017.06.005

Figure 6. Chemogenetic silencing of TRPV1-lineage neurons attenuates spontaneous and bite-evoked pain during masseter inflammation.

Figure 6

Averaged MGS scores (A) and bite force (B) evaluated before or after bilateral masseter injection of CNO (20 µg in 20 µl per side) after 1day following bilateral masseter injection of CFA in TRPV1-hM4Di or TRPV1-Cre mice. MGS was evaluated after 30 min and bite force was evaluated after 1 hour following bilateral masseter CNO injection. **p<0.001, #p<0.0001, +p<0.0001 versus respective base; post-hoc test following two-way ANOVA.