Table 2.
Thyroid grade | Standard | Expected |
activity | Outcome of therapy | |
0 | 185 Mbq | 85% cure and less than |
Not easily visible even with neck | ||
extension. Just palpable (Est 10 g) | 10% hypothyroid at 1 | |
I | 259 MBq | year. |
Visible only with neck extension but easily | ||
Palpable (Est 20 g) | ||
II | 370 MBq | |
Visible without neck extension (Est 40 g) | ||
III | 444 MBq | |
Visible easily from afar (Est 80 g) |
Adapted from the data of Zaini et al 1992 [68]. Only palpation was used to decide dosing in this study. The assumption made is that grades I - II goiters have median weights of 20–40 g [76], with the grade 0 goiter having a median weight of about 8 g [76,77] and grade III goiters a median weight of 80–100 g. [76] This regimen needs to be formally evaluated, especially in a study that uses a more accurate method of thyroid size assessment.