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. 2017 Oct 24;8:1387. doi: 10.3389/fimmu.2017.01387

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Copyright © 2017 Habir, Aeinehband, Wermeling and Malin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Normal antibody production against phosphocholine requires Arid3a. (A) Enzyme-Linked ImmunoSorbent Assay measurements of anti-phosphocholine IgM in naïve mice from the indicated genotypes n = 15–28 for each group. (B) Anti-phosphocholine IgM levels 14 days after PC-KLH immunization n = 4–5 for each group. (C) Absolute number of cells with a germinal center phenotype (CD19⁺B220⁺IgD⁻GL7⁺CD95⁺) in spleen, Peyer’s patches, and mesenteric lymph nodes after immunization with PC-KLH/Alum. n = 4–6 for each group. p-Values determined by Student’s t-test.