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. 2017 Oct 24;10:337. doi: 10.3389/fnmol.2017.00337

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Copyright © 2017 Capitanio, Moriggi, De Palma, Bizzotto, Molon, Torretta, Fania, Bonaldo, Gelfi and Braghetta.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative line charts and immunoblotting images of microtubule-associated proteins 1A/1B light chain 3 B (LC3B) and Beclin-1 in 6-, 12- and 24-month-old Col6a1^−/− (blue line) and wt (red line) diaphragm. Blot images have been spliced for a better visualization, full-length images are available in supplementary material (Supplementary Figures S1D,F). Variations are expressed as band intensities (arbitrary units). The asterisks mark significant differences in Col6a1^−/− mice compared to the respective age-matched Wt mice (Student’s t-test; n = 2; *p < 0.05). Bars below the charts represent significant differences (ANOVA and Tukey; n = 2; p < 0.05) between timepoints in Wt (red) and Col6a1^−/− (blue) mice.