Table 5.

Incidence and severity of histologic aortic mineralization

Animals examined	Adenine-free (n = 24)	Adenine diet
		Vehicle (n = 24)	Etelcalcetide (n = 23)	Paricalcitol (n = 24)
No mineralization	24	15	23	13
Minimum	0	1	0	0
Mild	0	2	0	1
Moderate	0	0	0	2
Marked	0	6	0	8
Total incidence	0	9/24 (38%)	0	11/24 (46%)

Semiquantitative histologic scoring of aortic wall mineralization: minimal = focal patchy vascular mineralization of tunica media detectible, mild = up to 10% of total specimen mineralized, moderate = 10–50% of specimen mineralized, Marked >50% of specimen mineralized