Table 1.

Literature review of other reported cases of advanced cystic adenoid carcinoma of the breast

Cases	Patient (age (years)/gender)	Distant metastasis	Treatment	Survival/prognostic	Time to relapse
Herzberg et al. [9]	57, female	Kidney	Mastectomy/nephrectomy	5-year disease-free survival, then lost to follow-up	Distant relapse: 6 years
Vranic et al. [10]	76, female	Kidney	Mastectomy/radical nephrectomy	No information after relapse	Distant relapse: 5 years
Koller et al. [11]	49, female	Brain, lungs	Breast surgery/Chemotherapy/radiation/left parieto-occipital craniotomy	No relapse at 20 months from the surgery	Local relapse: 1 year. Distant relapse: 8 years
Silva et al. [12]	37, female	Brain, liver, lungs, bone	Radical mastectomy/adjuvant chemotherapy (six cycles of adriamycin and cyclophosphamide)/radiotherapy/palliative chemotherapy (docetaxel plus vinorelbine and 5FU in second line)	The patient died 1 year after developing brain metastasis	Distant relapse: 2 years
Our case	65, female	Brain, lung, kidney	Mastectomy/palliative chemotherapy (mitoxantrone)/thoracotomy/radical nephrectomy/craniotomy plus radiotherapy	Patient still alive, now presenting liver lesions	Local relapse: 4 years. Distant relapses: 5 years

5FU 5-fluorouracil