Table 3.
Associations between MRI volumes and LASSI-L and other memory measures for 38 cognitively normal participants
| LASSI-L A2 (Maximum Storage) | LASSI-B1 (Vulnerable (to Proactive (Interference) Proactive | LASSI-B2 (Vulnerable to Recovery from Interference) | HVLT-R Total Recall | HVLT-R Delayed Recall | NACC Delayed Passages | |
|---|---|---|---|---|---|---|
| Hippocampal Volume | rs = 0.18 | rs = 0.28* | rs = 0.28* | rs = 0.07 | rs = 0.23 | rs = −0.33* |
| Inferior Lateral Ventricle | rs = −0.33* | rs = −0.49*** | rs = −0.57*** | rs = −0.39** | rs = −0.48*** | rs = −0.28* |
| Precuneus Volume | rs = 0.12 | rs = 0.15 | rs = 0.15 | rs = 0.21 | rs = 0.07 | rs = −0.25 |
| Inferior Temporal Volume | rs = −0.56 | rs = 0.004 | rs = −0.02 | rs = −0.02 | rs = −0.08 | rs = −0.25 |
| Superior Parietal Lobe Volume | rs = 0.14 | rs = 0.27* | rs = 0.21 | rs = 0.22 | rs = 0.23 | rs = −0.01 |
| Superior Frontal Volume | rs = 0.26 | rs = 0.19 | rs = 0.19 | rs = 0.22 | rs = 0.23 | rs = −0.14 |
| ERC Volume | rs = 0.26 | rs = 0.14 | rs = 0.11 | rs = 0.03 | rs = 0.21 | rs = −0.04 |
| Posterior Cingulate Volume | rs = 0.09 | rs = 0.26 | rs = 0.24 | rs = 0.05 | rs = 0.12 | rs = −0.27 |
| Temporal Pole Volume | rs = 0.20 | rs = 0.06 | rs = 0.20 | rs = 0.08 | rs = 0.12 | rs = −0.02 |
| Middle Frontal Volume | rs = −0.16 | rs = 0.11 | rs = 0.17 | rs = 0.16 | rs = 0.17 | rs = −0.12 |
Correlation coefficients represent Spearman Rank Order Correlation Coefficients. Due to multiple contrasts and to reduce the possibility of family-wise Type 1errors, the criteria for statistical significance is **p ≤ 0.01. LASSI-L, Loewenstein-Acevedo Scales for Semantic Interference and Learning; HVLT-R, Hopkins Verbal Learning Test-Revised; NACC, National Alzheimer’s Coordinating Center; ERC, entorhinal cortex.
p ≤ 0.05,
p ≤ 0.001.