Percentage of the maximum possible effects of oxycodone alone and in combination with large doses of verapamil (top left, n = 6) or nimodipine (bottom left, n = 6), and acetaminophen alone and in combination with verapamil (right, n = 6) on CFA-induced mechanical nociception. Ordinates: mean (± SEM) percentage of maximum possible effects; abscissa: oxycodone or acetaminophen dose (mg/kg, i.p.).