Table 1.

Comparison of RRP size, vesicle replenishment, release probability and short-term depression at the endbulb of Held synapse in PicWT and PicMut mice.

q: quantal size, taken from mEPSC amplitude; RRP: readily releasable pool; Repl.: replenishment rate of vesicles; P_r: release probability; EPSC_30–50/EPSC₁: average amplitude of EPSC30–50 normalized to the amplitude of EPSC1; τ: time constant of a single exponential fit to the decay of evoked EPSC amplitudes during train stimulation. Data presented as mean ± SEM, and medians in parentheses. Statistical significance between groups was determined by either unpaired Student’s t-test (in case of normally distributed data with comparable variances between the groups, T) or Wilcoxon rank sum test (when data distribution did not satisfy the criteria, W). Normality of distribution was tested with Jarque-Bera test and variances were compared with F-test. p-value < 0.05 signifying statistical significance in bold.