Table 5.

Top 10 DEGs and pathways between sham-injury and injury in different sections. By processing data from all time points in each section, top 10 DEGs and pathways between sham-injury and injury are showed, respectively.

Section	Top 10 DEGs between sham-injury and injury	Top 10 pathways between sham-injury and injury
rostral regions	Ccl3, Plek, Slc15a3, Bcl2a1a, Plek, Tlr2, Ccl4, Clec7a, Plek, Palld	Osteoclast differentiation, cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, phagosome, Chagas disease (American trypanosomiasis), leishmaniasis, toll-like receptor signaling pathway, chemokine signaling pathway, tuberculosis, transcriptional misregulation in cancer
lesion centre	Ccl3, Atf3, Plek, Ctla2b, Bcl2a1a, Ch25h, Plek, Tnfaip3, Tgif1, Gpr84	MAPK signaling pathway, metabolic pathways, PI3K-Akt signaling pathway, pathways in cancer, osteoclast differentiation, HTLV-I infection, regulation of actin cytoskeleton, chemokine signaling pathway, Focal adhesion, proteoglycans in cancer
caudal regions	Atf3, Tlr2, Irgm1, Trim30d, S1pr3, Bcl2a1a, Slc45a3, Plek, Trim30a, Zfp36l1	Tuberculosis, phagosome, Staphylococcus aureus infection, leishmaniasis, osteoclast differentiation, antigen processing and presentation, herpes simplex infection, Fc gamma R-mediated phagocytosis, viral myocarditis, Toll-like receptor signaling pathway