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. 2017 May 19;21(11):2863–2871. doi: 10.1111/jcmm.13199

Figure 5.

Figure 5

The effect of telocytes (TCs) on spleen CD4+ T cell. Flow cytometry showed that the proportion of spleen CD4 + T‐cell subgroup (A). TCs significantly decreased the proportion of CD4 + IL‐4+ T cells (B) and increased the proportion of CD4 + IFN‐γ+ T cells (C) and CD4 + Foxp3+ T cells (D). TCs could significantly decrease GATA‐3 mRNA (E) and increase T‐bet mRNA (F) and Foxp3 mRNA (G) in spleen CD4+ T cells. There was no statistical difference between TCs group in two doses. Combination TCs with mesenchymal stem cells (MSC) could more obviously decreased the proportion of CD4 + IL‐4+ T cells and the GATA‐3 expression (n = 6/group). *P < 0.05 versus PBS group; #P < 0.05 versus ovalbumin (OVA) group; +P < 0.05 versus TCs + MSC group.