Table 1.

Correlation between HIF‐2α expression and clinicopathological characteristics of PDAC patients

Characteristics	Patient frequency (%)	HIF‐2α level
		Low	High	P value†
Total cases	283	135	148
Gender
Male	167	80	87	0.935
Female	116	55	61
Age
<60	126	61	65	0.593
≥60	157	71	86
Differentiation
Well	77	50	27	0.001**
Moderate	123	62	61
Poor	83	23	60
TNM stage(AJCC)
I	24	14	10	0.006**
II	172	93	79
III	23	7	16
IV	64	21	43
T stage
T1	4	4	0	0.024*
T2	33	19	14
T3	211	102	109
T4	35	11	24
Lymph‐node metastasis
Negative	113	66	47	0.003**
Positive	170	69	101
Perineural invasion
Negative	133	82	51	0.001**
Positive	150	63	87

^†Chi‐square test, *P < 0.05, **P < 0.01.