Table 2.

Multivariate Cox regression analyses of OS and PFS in PDAC patients

Variables	Hazard Ratio	Std. Err.	z	P > z	95% Conf. Interval
Overall survival
Gender	0.819069	0.118835	−1.38	0.169	0.616344	1.088473
Age	1.085215	0.164879	0.54	0.59	0.805732	1.461641
Differentiation	0.861365	0.083491	−1.54	0.124	0.71233	1.04158
TNM stage (AJCC)	1.962722	0.359883	3.68	0.003**	1.370197	2.811476
Lymph‐node metastasis	1.259477	0.20096	1.45	0.148	0.921242	1.721895
Perineural invasion	0.584926	0.222848	−1.41	0.159	0.277208	1.23423
HIF‐2α level	1.418071	0.217761	2.27	0.023*	1.049509	1.916061
Progression‐free survival
Gender	0.912942	0.131993	−0.63	0.529	0.687664	1.212021
Age	0.874395	0.134805	−0.87	0.384	0.646366	1.182869
Differentiation	0.840913	0.081486	−1.79	0.074	0.695454	1.016796
TNM stage (AJCC)	1.79714	0.333591	3.16	0.002**	1.249047	2.58574
Lymph‐node metastasis	1.417982	0.225453	2.2	0.028*	1.038325	1.936459
Perineural invasion	0.724537	0.280056	−0.83	0.404	0.339661	1.545525
HIF‐2α level	1.358757	0.208601	2	0.046*	1.005685	1.835783

*P < 0.05, **P < 0.01.