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. 2017 May 30;21(11):3023–3043. doi: 10.1111/jcmm.13213

Figure 6.

Figure 6

MiR‐384 and PTN affect cell proliferation, colony formation, invasion and metastasis in vitro, and miR‐384 and PTN affect tumour growth in vivo. (A) miR‐384 could inhibit the colony formation and invasion ability of Huh‐7 compared with control cells. Anti‐miR‐384 and PTN increased the colony formation and invasion ability of Huh‐7 cells compared with the controls. (B) miR‐384 could inhibit the metastasis ability of Huh‐7 cells compared with the controls. Anti‐miR‐384 and PTN increased the metastasis ability of Huh‐7 cells compared with the controls. (C) The cell growth curve clearly showed decreased proliferation in Huh‐7‐ miR‐384 compared with Huh‐7‐NC cells. Huh‐7‐anti‐miR‐384 displayed increased proliferation compared with Huh‐7‐NC cells. (D) The tumour volume in the PTN overexpression group was significantly greater than that in the control group. The tumour nodule volume in the miR‐384 overexpression group was significantly smaller than that in the control group.