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. 2017 May 30;21(11):3023–3043. doi: 10.1111/jcmm.13213

Table 1.

Correlation between the clinicopathological characteristics and miR‐384 and PTN expression in HCC

Pathological factors n No. of patients No. of patients
miR‐384 miR‐384 P PTN PTN P
Low High Negative (−, ±) Positive (+, ++)
Total no. of patients 80 51 29 33 47
Age (years)
<50 32 18 14 >0.05 13 19 >0.05
≥50 48 33 15 20 28
Sex
Male 61 39 22 >0.05 25 36 >0.05
Female 19 12 7 8 11
HBV
Absent 17 7 10 <0.05a 11 6 <0.05a
Present 63 44 19 22 41
Tumour size (cm)
<5 28 15 13 >0.05 12 16 >0.05
≥5 52 36 16 21 31
Cirrhosis
Absent 23 12 11 >0.05 14 9 <0.05a
Present 57 39 18 19 38
Adjacent organ invasion
Absent 60 34 26 <0.05a 29 31 <0.05a
Present 20 17 3 4 16
Microscopic vascular invasion
Absent 57 32 25 <0.05a 28 29 <0.05a
Present 23 19 4 5 18
PVTT
Absent 65 43 22 >0.05 27 38 >0.05
Present 15 8 7 6 9
TNM tumour stage
I + II 55 32 27 <0.05a 30 25 <0.05a
III + IV 25 23 2 3 22
AFP
≤400 49 33 16 >0.05 17 32 >0.05
>400 31 18 13 16 15

HCC: hepatocellular carcinoma; HBV: hepatitis B virus; TNM: tumour node metastasis; PVTT: portal vein tumour thrombus; ‘−‘and ‘±’, negative; ‘+’ and ‘++’, positive.

a

P < 0.05 was considered statistically significant.