Figure 4.

The 6-OHDA lesions alter step sequence preference. (A) Schematic demonstrates the order of each paw in the six-step sequence pattern classifications. (B) Overall step sequence: the proportions of each step sequence type out of total step patterns identified. (C) The cruciate A step sequence is more common after lesion, permitting quantification of parkinsonian gait in an animal model. LF, left front paw; LH, left hind paw; RF, right front paw; RH, right hind paw; 6-OHDA, 6-hydroxydopamine; Intra-STR, group with injections of 6-OHDA in the striatum; MFB, medial forebrain bundle/group with injections of 6-OHDA in the medial forebrain bundle.