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. 2017 Apr 1;26(4):659–667. doi: 10.3727/096368916X693059

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Figure 5. — Correlation of step sequence and TH immunoreactivity in the midbrain. To examine the relationship between TH staining and changes in gait, optical density of TH staining in the midbrain was correlated to (A) the percentage of steps taken in the alternate sequences and (B) in the cruciate sequences on week 6. Although negative and positive correlations are shown with TH staining/alternate step sequences and TH staining/cruciate step sequences, respectively, a floor effect (0% of alternate sequence in MFB lesion) and a ceiling effect (100% steps taken as alternate in sham lesion) negate statistical analysis. TH, tyrosine hydroxylase; 6-OHDA, 6-hydroxydopamine; Intra-STR, group with injections of 6-OHDA in the striatum; MFB, medial forebrain bundle/group with injections of 6-OHDA in the medial forebrain bundle.