Table 1.
The correlation of miR‐30e expression with clinicopathologic characteristics of LAC patients
| Variables | Cases (n) | miR‐30e | P value | |
|---|---|---|---|---|
| High | Low | |||
| Total | 78 | 53 | 25 | |
| Age (years) | ||||
| ≥60 | 32 | 24 | 8 | 0.269 |
| <60 | 46 | 29 | 17 | |
| Sex | ||||
| Male | 51 | 35 | 16 | 0.861 |
| Female | 27 | 18 | 9 | |
| Smoking status | ||||
| Current smokers | 12 | 7 | 5 | 0.697 |
| Previous smokers | 45 | 32 | 13 | |
| Slight/No smokers | 21 | 14 | 7 | |
| Tumour size (cm) | ||||
| ≥3 | 36 | 29 | 7 | 0.028 |
| <3 | 42 | 24 | 18 | |
| Adenocarcinoma subtypes | ||||
| Adenocarcinoma in situ (AIS) | 3 | 0 | 3 | |
| Minimally invasive adenocarcinoma (MIA) | 7 | 3 | 4 | |
| Invasive adenocarcinoma | ||||
| Lepidic predominant | 37 | 28 | 9 | 0.067 |
| Acinar predominant | 14 | 9 | 5 | |
| Papillary predominant | 11 | 9 | 2 | |
| Variants of invasive adenocarcinoma | ||||
| Invasive mucinous adenocarcinoma (IMA) | 6 | 4 | 2 | |
| Pathological stage | ||||
| I/II | 57 | 36 | 21 | 0.138 |
| Ш/IV | 21 | 17 | 4 | |
| pT stage | ||||
| T1/T2 | 66 | 46 | 20 | 0.441 |
| T3/T4 | 12 | 7 | 5 | |
| pN stage | ||||
| Negative | 43 | 29 | 14 | 0.916 |
| Positive | 35 | 24 | 11 | |
| pM stage | ||||
| Negative | 69 | 48 | 21 | 0.400 |
| Positive | 9 | 5 | 4 | |